Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.43 |
| ▸ | AQP1 | P29972 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565529 | 1.00 | NPY5R (0.44) | NPY5RADRA2ATLR7MCHR1AQP1 | |
| SCHEMBL13565916 | 0.84 | NPY5R (0.44) | NPY5RADRA2ATLR7MCHR1AQP1 | |
| SCHEMBL13565396 | 0.84 | CYP2C19 (0.45) | NPY5RADRA2AMCHR1MAPTKMT2A | |
| SCHEMBL17090306 | 0.84 | CYP2C19 (0.45) | NPY5RADRA2AMCHR1MAPTKMT2A | |
| SCHEMBL11935223 | 0.81 | CRHR1 (0.44) | NPY5RADRA2AMCHR1ALDH1A1KMT2A | |
| SCHEMBL13438902 | 0.81 | CRHR1 (0.44) | NPY5RADRA2AMCHR1ALDH1A1KMT2A | |
| SCHEMBL11936318 | 0.81 | RAB9A (0.43) | ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL13439078 | 0.79 | NPC1 (0.47) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11935361 | 0.79 | NPC1 (0.47) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14424735 | 0.78 | NPY5R (0.53) | NPY5RALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |