Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935242 | 1.00 | DRD2 (0.44) | DRD2ADRA1DADRA1AADRA1BCNR2 | |
| SCHEMBL17090014 | 0.85 | ALDH1A1 (0.43) | BRD4MEN1KMT2AMAPTKCNT1 | |
| SCHEMBL13566011 | 0.85 | ALDH1A1 (0.43) | BRD4MEN1KMT2AMAPTKCNT1 | |
| SCHEMBL17089986 | 0.84 | CNR2 (0.47) | CNR2TSHR | |
| SCHEMBL13565699 | 0.84 | CNR2 (0.47) | CNR2TSHR | |
| SCHEMBL13564856 | 0.83 | ACHE (0.42) | DRD2ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL17090107 | 0.83 | ACHE (0.42) | DRD2ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL17089994 | 0.81 | ACHE (0.49) | DRD2ADRA1DADRA1AADRA1BCNR2 | |
| SCHEMBL13564870 | 0.81 | ACHE (0.49) | DRD2ADRA1DADRA1AADRA1BCNR2 | |
| SCHEMBL17090335 | 0.80 | TDP1 (0.42) | CNR2KMT2AL3MBTL1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |