Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565148 | 1.00 | DRD2 (0.40) | DRD2MAPTOPRM1OPRL1JAK1 | |
| SCHEMBL13565097 | 0.88 | OPRM1 (0.39) | DRD2OPRM1OPRL1JAK1CCR1 | |
| SCHEMBL11940763 | 0.84 | OPRM1 (0.40) | DRD2OPRM1OPRL1JAK1CHRM4 | |
| SCHEMBL13438971 | 0.84 | OPRM1 (0.40) | DRD2OPRM1OPRL1JAK1CHRM4 | |
| SCHEMBL13565578 | 0.84 | CNR2 (0.41) | — | |
| SCHEMBL17090008 | 0.84 | CNR2 (0.41) | — | |
| SCHEMBL10116248 | 0.84 | L3MBTL1 (0.47) | DRD2MAPTCCR1DRD3 | |
| SCHEMBL10114422 | 0.84 | L3MBTL1 (0.47) | DRD2MAPTCCR1DRD3 | |
| SCHEMBL13565547 | 0.83 | NPC1 (0.45) | JAK1 | |
| SCHEMBL17090165 | 0.83 | NPC1 (0.45) | JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |