Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935083 | 0.99 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL13564972 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL11935094 | 0.91 | HDAC3 (0.46) | ALDH1A1L3MBTL1GAANPY5RUSP30 | |
| SCHEMBL17090123 | 0.91 | DRD2 (0.43) | GFERMAPTGAAALOX15MAPK1 | |
| SCHEMBL13565564 | 0.91 | DRD2 (0.43) | GFERMAPTGAAALOX15MAPK1 | |
| SCHEMBL17090135 | 0.91 | HDAC3 (0.46) | ALDH1A1L3MBTL1GAANPY5RUSP30 | |
| SCHEMBL11935093 | 0.91 | MAPT (0.45) | ALDH1A1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL17090124 | 0.91 | L3MBTL3 (0.44) | ALDH1A1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL13565504 | 0.91 | L3MBTL3 (0.44) | ALDH1A1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL13564874 | 0.90 | NPY5R (0.36) | ALDH1A1KDM4EL3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |