Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565602 | 0.90 | SLC22A12 (0.44) | KIF11PPARANR3C1CNR2AR | |
| SCHEMBL13565062 | 0.88 | PPARA (0.44) | KIF11PPARANR3C1CNR2AR | |
| SCHEMBL13565952 | 0.87 | PPARA (0.41) | KIF11PPARANR3C1CNR2AR | |
| SCHEMBL13565337 | 0.86 | PPARA (0.42) | KIF11PPARAADRA2AHIF1AEPHX2 | |
| SCHEMBL13565078 | 0.86 | MAPT (0.45) | PPARAHIF1A | |
| SCHEMBL17090248 | 0.84 | KIF11 (0.49) | KIF11CNR2ARSLC22A12P2RX7 | |
| SCHEMBL13565693 | 0.84 | MAPT (0.42) | PPARAHIF1A | |
| SCHEMBL11936147 | 0.83 | UTS2R (0.41) | PPARAUTS2RHIF1AFFAR4 | |
| SCHEMBL13565993 | 0.81 | PPARA (0.55) | KIF11PPARAADRA2AFFAR1 | |
| SCHEMBL11936067 | 0.81 | CA1 (0.45) | HIF1AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |