Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090273 | 0.85 | EPHX1 (0.32) | GRIA1EPHX1 | |
| SCHEMBL10115464 | 0.84 | GRIA1 (0.42) | GRIA1NPY5RFABP4 | |
| SCHEMBL13439365 | 0.82 | GRIA1 (0.43) | GRIA1NPY5RHTR1AFABP4 | |
| SCHEMBL11935695 | 0.81 | PAOX (0.37) | EPHX1 | |
| SCHEMBL13564980 | 0.75 | GRIA1 (0.43) | GRIA1NPY5RHTR1A | |
| SCHEMBL17090287 | 0.75 | GRIA1 (0.43) | GRIA1NPY5RHTR1AFABP4 | |
| SCHEMBL13565322 | 0.74 | GRIA1 (0.49) | GRIA1NPY5R | |
| SCHEMBL17090215 | 0.73 | GRIA1 (0.44) | GRIA1NPY5RHTR1AFABP4 | |
| SCHEMBL17090450 | 0.72 | GRIA1 (0.43) | GRIA1NPY5R | |
| SCHEMBL17090485 | 0.71 | PPARA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |