Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935634 | 0.86 | TAS1R3 (0.37) | TAS1R3TAS1R1CREBBPBRD4MAPT | |
| SCHEMBL10115388 | 0.85 | HDAC6 (0.45) | GRIA1TAS1R3TAS1R1MAPTFABP4 | |
| SCHEMBL11935774 | 0.84 | NPSR1 (0.45) | GRIA1NPY5RNR3C1HTR1ACTSL | |
| SCHEMBL11935795 | 0.83 | TAS1R3 (0.41) | TAS1R3TAS1R1CREBBPBRD4MAPT | |
| SCHEMBL13565322 | 0.83 | GRIA1 (0.49) | GRIA1NPY5RGRIA2CTSLCTSS | |
| SCHEMBL17090450 | 0.78 | GRIA1 (0.43) | GRIA1NPY5RTAS1R3TAS1R1NR3C1 | |
| SCHEMBL17090287 | 0.78 | GRIA1 (0.43) | GRIA1NPY5RNR3C1HTR1AFABP4 | |
| SCHEMBL17090463 | 0.75 | LMNA (0.41) | TAS1R3TAS1R1NR3C1 | |
| SCHEMBL13439365 | 0.74 | GRIA1 (0.43) | GRIA1NPY5RHTR1AFABP4 | |
| SCHEMBL17090288 | 0.73 | GRIA1 (0.49) | GRIA1NPY5RHTR1AFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |