Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090288 | 0.85 | GRIA1 (0.49) | EPHX1GRIA1 | |
| SCHEMBL10115148 | 0.85 | ALDH1A1 (0.38) | — | |
| SCHEMBL17090272 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL11935695 | 0.79 | PAOX (0.37) | EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17090276 | 0.76 | CISD1 (0.34) | — | |
| SCHEMBL11935627 | 0.76 | LMNA (0.36) | — | |
| SCHEMBL13565343 | 0.76 | MLYCD (0.45) | — | |
| SCHEMBL11935634 | 0.74 | TAS1R3 (0.37) | TAS1R3TAS1R1 | |
| SCHEMBL11935350 | 0.74 | BRD4 (0.38) | TAS1R3TAS1R1 | |
| SCHEMBL11935606 | 0.72 | NPSR1 (0.46) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |