Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090276 | 0.87 | CISD1 (0.34) | NR3C1CISD1FABP4 | |
| SCHEMBL10115460 | 0.86 | ALDH1A1 (0.39) | GRIA1NR3C1FABP4 | |
| SCHEMBL13564980 | 0.84 | GRIA1 (0.43) | GRIA1NPY5RHTR1A | |
| SCHEMBL11935696 | 0.83 | ROCK1 (0.41) | — | |
| SCHEMBL13439365 | 0.82 | GRIA1 (0.43) | GRIA1NPY5RCISD1FABP4HTR1A | |
| SCHEMBL17090215 | 0.78 | GRIA1 (0.44) | GRIA1NPY5RNR3C1FABP4HTR1A | |
| SCHEMBL17090450 | 0.77 | GRIA1 (0.43) | GRIA1NPY5RNR3C1 | |
| SCHEMBL17090288 | 0.75 | GRIA1 (0.49) | GRIA1NPY5RFABP4HTR1A | |
| SCHEMBL17090505 | 0.75 | NR3C1 (0.39) | NR3C1 | |
| SCHEMBL17090544 | 0.73 | MAPK14 (0.37) | NPY5RNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |