Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090102 | 0.86 | PTPN1 (0.44) | PTPN1KMT2AMGLLNPC1LMNA | |
| SCHEMBL17090069 | 0.86 | PKM (0.44) | KMT2AMGLLNPC1LMNAPKM | |
| SCHEMBL13203848 | 0.85 | MDM2 (0.51) | PTPN1KMT2AMGLLNPC1LMNA | |
| SCHEMBL10113310 | 0.85 | MDM2 (0.51) | PTPN1KMT2AMGLLNPC1LMNA | |
| SCHEMBL13203728 | 0.77 | MDM2 (0.71) | PTPN1KMT2ANPC1LMNAPKM | |
| SCHEMBL10113120 | 0.77 | MDM2 (0.71) | PTPN1KMT2ANPC1LMNAPKM | |
| SCHEMBL13565094 | 0.76 | NPY5R (0.50) | — | |
| SCHEMBL13564976 | 0.76 | MEN1 (0.33) | KMT2AHPGD | |
| SCHEMBL17089975 | 0.76 | PTPN1 (0.47) | PTPN1KMT2AMGLLNPC1LMNA | |
| SCHEMBL13565540 | 0.73 | CNR2 (0.43) | KMT2ANPC1LMNARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |