Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565187 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4ERECQLCYP3A4 | |
| SCHEMBL17090360 | 0.87 | POLB (0.44) | ALDH1A1SMN1; SMN2KDM4ERECQLCYP3A4 | |
| SCHEMBL13565128 | 0.87 | POLB (0.44) | ALDH1A1SMN1; SMN2KDM4ERECQLCYP3A4 | |
| SCHEMBL13565108 | 0.87 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4ERECQLCYP3A4 | |
| SCHEMBL17090353 | 0.87 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4ERECQLCYP3A4 | |
| SCHEMBL11935336 | 0.85 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAHTTALDH3A1 | |
| SCHEMBL13439059 | 0.85 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAHTTALDH3A1 | |
| SCHEMBL17090423 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4ERECQLCYP3A4 | |
| SCHEMBL13565240 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4ERECQLCYP3A4 | |
| SCHEMBL13565152 | 0.83 | LMNA (0.45) | ALDH1A1SMN1; SMN2LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |