Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565853 | 1.00 | GRIA4 (0.42) | GRIA4CA1CA2ALDH1A1ALDH3A1 | |
| SCHEMBL13565594 | 0.90 | CRHR1 (0.36) | ALDH1A1ALDH3A1GRIA2CNR2NPY5R | |
| SCHEMBL17090163 | 0.90 | CRHR1 (0.36) | ALDH1A1ALDH3A1GRIA2CNR2NPY5R | |
| SCHEMBL11936150 | 0.89 | CRHR1 (0.43) | EPHX2GRIA2CNR2NPY5RCRHR1 | |
| SCHEMBL11935326 | 0.89 | CRHR1 (0.43) | EPHX2GRIA2CNR2NPY5RCRHR1 | |
| SCHEMBL13565459 | 0.86 | CRHR1 (0.40) | GRIA4ALDH1A1ALDH3A1GRIA2NPY5R | |
| SCHEMBL17090159 | 0.86 | CRHR1 (0.40) | GRIA4ALDH1A1ALDH3A1GRIA2NPY5R | |
| SCHEMBL13565147 | 0.86 | GRIA4 (0.45) | GRIA4ALDH1A1ALDH3A1GRIA2NPY5R | |
| SCHEMBL17090377 | 0.86 | GRIA4 (0.45) | GRIA4ALDH1A1ALDH3A1GRIA2NPY5R | |
| SCHEMBL17090161 | 0.85 | ALDH1A1 (0.36) | ALDH1A1ALDH3A1GRIA2CNR2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |