⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15204059 | 0.80 | — | — | |
| SCHEMBL11226080 | 0.76 | CA5A (0.33) | — | |
| SCHEMBL3277141 | 0.71 | — | — | |
| SCHEMBL10031061 | 0.69 | — | — | |
| SCHEMBL16500014 | 0.69 | — | — | |
| SCHEMBL25205965 | 0.67 | — | — | |
| SCHEMBL313192 | 0.65 | — | — | |
| SCHEMBL1709053 | 0.65 | — | — | |
| SCHEMBL5354 | 0.64 | — | — | |
| Bromide SCHEMBL5839228 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141335-B1 | CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS | GENENCOR INT (US) | 2009-08-05 | — | — | EP | disclosed |
| US-7371553-B2 | Chemically modified enzymes with multiple charged variants | GENENCOR INTERNATIONAL, INC. (US) | 2008-05-13 | — | — | US | disclosed |
| US-20050089966-A1 | Chemically modified enzymes with multiple charged variants | DAVID BENJAMIN G (GB) | 2005-04-28 | — | — | US | disclosed |
| US-20020127695-A1 | Chemically modified enzymes with multiple charged variants | GENENCOR INTERNATIONAL, INC. | 2002-09-12 | — | — | US | disclosed |
| US-6379942-B1 | SUBTILISIN ENZYME, WITH CYSTEINE RESIDUES AT GIVE AMINO ACID SEQUENCE POSITIONS, WHERE THE THIOL HYDROGEN IN THE CYSTEINE RESIDUE IS REPLACED, PROVIDING A SIDE CHAIN IWTH A MULTIPLY CHARGED MOIETY; DETERGENTS | GENENCOR INTERNATIONAL, INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1141335-A2 | CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS | GENENCOR INTERNATIONAL, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037658-A2 | CHEMICALLY MODIFIED ENZYMES WITH MULTIPLE CHARGED VARIANTS | GENENCOR INTERNATIONAL, INC. (US) | 2000-06-29 | — | — | WO | disclosed |