Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439238 | 0.84 | MAPK14 (0.39) | MAPK14NPY5RPTGER4 | |
| SCHEMBL11935496 | 0.84 | MAPK14 (0.39) | MAPK14NPY5RPTGER4 | |
| SCHEMBL13439191 | 0.82 | MAPK14 (0.43) | MAPK14NPY5R | |
| SCHEMBL11935456 | 0.82 | MAPK14 (0.43) | MAPK14NPY5R | |
| SCHEMBL11935506 | 0.81 | MAPK14 (0.37) | MAPK14PTGER4 | |
| SCHEMBL13439239 | 0.81 | MAPK14 (0.37) | MAPK14PTGER4 | |
| SCHEMBL10114928 | 0.81 | GRIA2 (0.33) | NPY5R | |
| SCHEMBL13204430 | 0.81 | GRIA2 (0.33) | NPY5R | |
| SCHEMBL17090544 | 0.78 | MAPK14 (0.37) | MAPK14NPY5RPTGER4 | |
| SCHEMBL17090366 | 0.77 | MAPK14 (0.45) | MAPK14NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |