Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746326 | 0.87 | SMN1; SMN2 (0.54) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL10379455 | 0.87 | TSHR (0.48) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL669346 | 0.86 | SMN1; SMN2 (0.57) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL27930527 | 0.85 | MAPT (0.43) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL22904171 | 0.85 | TLR8 (0.57) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL620699 | 0.85 | GAA (0.45) | MAPTGAAPOLBKMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28193306 | 0.85 | SMN1; SMN2 (0.56) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL192392 | 0.85 | MAPT (0.43) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL2127539 | 0.85 | SLC6A4 (0.44) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL9745662 | 0.83 | SMN1; SMN2 (0.58) | MAPTGAAPOLBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139696-B1 | Aromatic diamines containing three ether-linked-benzonitrile moieties, polymers thereof, and methods of making the same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2015-09-22 | — | — | US | disclosed |