Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669346 | 0.96 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| Ammonia Solution, Strong SCHEMBL28193306 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9745478 | 0.93 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9745662 | 0.93 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL8626899 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EPOLBGAAALDH1A1 | |
| SCHEMBL9746110 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| Dimethylamine SCHEMBL1361903 | 0.90 | POLB (0.53) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9746273 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9746151 | 0.89 | SCN9A (0.48) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL17090701 | 0.87 | MAPT (0.47) | SMN1; SMN2KDM4EPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118431-A | Phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5061388-A | Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |