Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27966321 | 0.85 | FOLH1 (0.40) | — | |
| SCHEMBL27966162 | 0.85 | CNR2 (0.38) | — | |
| SCHEMBL12661112 | 0.83 | CTSK (0.45) | CTSKCTSS | |
| SCHEMBL16509160 | 0.82 | GAA (0.34) | GAA | |
| SCHEMBL16206243 | 0.81 | ZDHHC7 (0.44) | CTSKCTSS | |
| SCHEMBL14932839 | 0.81 | GABRR1 (0.34) | — | |
| SCHEMBL10167182 | 0.79 | EPHX1 (0.50) | GAA | |
| SCHEMBL14865083 | 0.79 | TGFBR1 (0.33) | GAA | |
| SCHEMBL890099 | 0.79 | CTSK (0.41) | CTSKGAACTSS | |
| SCHEMBL12630385 | 0.79 | CTSK (0.41) | CTSKGAACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139569-B2 | Fused tricyclic aryl compounds useful for the treatment of viral diseases | MERCK SHARP & DOHME CORP. (US) | 2015-09-22 | — | — | US | disclosed |