Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661112 | 0.94 | CTSK (0.45) | ZDHHC7EPHX1CTSKCTSSCA1 | |
| SCHEMBL12661111 | 0.86 | CTSK (0.41) | ZDHHC7EPHX1CTSKCTSSCA1 | |
| SCHEMBL890099 | 0.86 | CTSK (0.41) | ZDHHC7EPHX1CTSKCTSSCA1 | |
| SCHEMBL12630385 | 0.86 | CTSK (0.41) | ZDHHC7EPHX1CTSKCTSSCA1 | |
| SCHEMBL7123665 | 0.84 | NOD1 (0.57) | ZDHHC7EPHX1SIRT1NOD1MEN1 | |
| SCHEMBL29299766 | 0.83 | CTSK (0.61) | CTSKCTSS | |
| SCHEMBL18123014 | 0.83 | CTSK (0.61) | CTSKCTSS | |
| SCHEMBL20435333 | 0.82 | SIRT6 (0.55) | ZDHHC7SIRT1SIRT6PLA2G2ANOD1 | |
| SCHEMBL14978808 | 0.82 | SIRT6 (0.55) | ZDHHC7SIRT1SIRT6PLA2G2ANOD1 | |
| SCHEMBL10167182 | 0.82 | EPHX1 (0.50) | EPHX1SIRT1SIRT6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9421275-B2 | Oligomer-calcimimetic conjugates and related compunds | NEKTAR THERAPEUTICS (US) | 2016-08-23 | — | — | US | disclosed |
| US-20140328791-A1 | Conjugates of an IL-2 Moiety and a Polymer | NEKTAR THERAPEUTICS | 2014-11-06 | — | — | US | disclosed |
| US-20140323565-A1 | Oligomer-Calcimimetic Conjugates and Related Compunds | NEKTAR THERAPEUTICS (US) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140328791-A1 | Conjugates of an IL-2 Moiety and a Polymer | IL2, IL2RA, ILF2 | ZDHHC7 1458/4885EPHX1 2620/4885CTSK 1672/4885 |
| US-20140323565-A1 | Oligomer-Calcimimetic Conjugates and Related Compunds | CALCR, CALCB, CALCA | ZDHHC7 3443/4885EPHX1 2587/4885CTSK 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.