SCHEMBL1709071

SCHEMBL1709071

O=C(Cc1ccc(CN2/C(=C/C=C/c3oc4ccccc4[n+]3Cc3ccc(CC(=O)ON4C(=O)CCC4=O)cc3)Oc3ccccc32)cc1)ON1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1709069 0.86 MAPT (0.36) L3MBTL1
SCHEMBL13966972 0.82 MAPT (0.37) L3MBTL1
SCHEMBL31551165 0.79 MEN1 (0.34) L3MBTL1
SCHEMBL14089210 0.72 MEN1 (0.33)
SCHEMBL1709074 0.71 FOLH1 (0.32)
SCHEMBL13966973 0.69 MAPT (0.52) L3MBTL1
SCHEMBL10068624 0.69 MEN1 (0.46) L3MBTL1
SCHEMBL10035959 0.69 MEN1 (0.46) L3MBTL1
SCHEMBL2410627 0.69 MEN1 (0.46) L3MBTL1
SCHEMBL12364496 0.69 MEN1 (0.46) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012048063-A2 CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE EMD MILLIPORE CORPORATION (US) 2012-04-12 WO disclosed
US-20120088262-A1 CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE MILLIPORE CORPORATION (US) 2012-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088262-A1 CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE CASP7, MCL1, CARS1 L3MBTL1 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.