SCHEMBL10035959

SCHEMBL10035959

CCN1/C(=C/C=C/c2oc3ccccc3[n+]2CC)Oc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 12/20 0.46
KMT2A Q03164 12/20 0.46
HTT P42858 8/20 0.46
KDM4E B2RXH2 6/20 0.46
MAPT P10636 6/20 0.46
RAB9A P51151 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
NPC1 O15118 4/20 0.46
THRB P10828 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
USP2 O75604 2/20 0.46
POLB P06746 2/20 0.46
CTNNB1 P35222 2/20 0.46
ABCB1 P08183 1/20 0.46
APEX1 P27695 1/20 0.46
ALDH1A1 P00352 5/20 0.46
LMNA P02545 4/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12364496 1.00 MEN1 (0.46) MEN1KMT2AHTTKDM4EMAPT
SCHEMBL30686974 1.00 MEN1 (0.46) MEN1KMT2AHTTKDM4EMAPT
SCHEMBL29358704 1.00 MEN1 (0.46) MEN1KMT2AHTTKDM4EMAPT
SCHEMBL10068624 1.00 MEN1 (0.46) MEN1KMT2AHTTKDM4EMAPT
SCHEMBL2410627 1.00 MEN1 (0.46) MEN1KMT2AHTTKDM4EMAPT
Iodide SCHEMBL457968 0.99 MEN1 (0.47) MEN1KMT2AHTTKDM4EMAPT
Iodide SCHEMBL32672581 0.99 MEN1 (0.47) MEN1KMT2AHTTKDM4EMAPT
Iodide SCHEMBL2464686 0.99 MEN1 (0.47) MEN1KMT2AHTTKDM4EMAPT
Iodide SCHEMBL457967 0.99 MEN1 (0.47) MEN1KMT2AHTTKDM4EMAPT
Iodide SCHEMBL29364175 0.99 MEN1 (0.47) MEN1KMT2AHTTKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA UNIV JEFFERSON (US) 2023-05-18 US disclosed
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA UNIV JEFFERSON (US) 2023-05-18 US disclosed
US-10780184-B2 Fluorescent solid lipid nanoparticles composition and preparation thereof BRACCO IMAGING S.P.A. (IT) 2020-09-22 US disclosed
US-20190167818-A1 FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF BRACCO IMAGING S.P.A. (IT) 2019-06-06 US disclosed
US-20170335086-A1 POLYMER COMPOSITIONS, SHRINK FILMS, AND METHODS OF MAKING THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-11-23 US disclosed
US-20170259541-A1 SHRINK FILMS, AND METHODS OF MAKING THEREOF DOW GLOBAL TECHNOLOGIES LLC 2017-09-14 US disclosed
US-9465290-B2 Near-infrared absorbing film compositions GLOBALFOUNDRIES INC. (KY) 2016-10-11 US disclosed
US-20160106869-A1 FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF BRACCO IMAGING S.P.A. (IT) 2016-04-21 US disclosed
US-20140210034-A1 NEAR-INFRARED ABSORBING FILM COMPOSITIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-31 US disclosed
US-8772376-B2 Near-infrared absorbing film compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-08 US disclosed
US-20110190480-A1 CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES IGNATYEV NIKOLAI MYKOLA 2011-08-04 US disclosed
US-20110042771-A1 Near-Infrared Absorbing Film Compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-02-24 US disclosed
US-7888506-B2 include a conjugated ring system, such as a dithiolone, a pyran, and a pyrazine containing ring system; biomarker applications, pH sensors, metal sensors, and as components for molecular electronics DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2011-02-15 US disclosed
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES ELITECHGROUP MDX LLC 2010-10-14 US disclosed
US-7767834-B2 Phosphonylated fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2010-08-03 US disclosed
US-7671218-B2 Phosphonate fluorescent dyes and conjugates Elitech Holdings B.V. (NL) 2010-03-02 US disclosed
US-20100041158-A1 Lead sensor and methods of use DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2010-02-18 US disclosed
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2008-08-28 US disclosed
US-20080182337-A1 COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF FLUOROPHORES DUQUESNE UNIVERSITY (US) 2008-07-31 US disclosed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 MEN1 1647/4885KMT2A 3091/4885HTT 1730/4885
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 MEN1 1539/4885KMT2A 3036/4885HTT 1743/4885
US-20110190480-A1 CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES ZAP70, MYLK3, KIT MEN1 4104/4885KMT2A 823/4885HTT 3056/4885
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA TFAM, COX5A, UQCRC1 MEN1 2633/4885KMT2A 3675/4885HTT 2179/4885
US-20190167818-A1 FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF PLIN3, LIPA, NPC1L1 MEN1 2166/4885KMT2A 2642/4885HTT 3819/4885
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 MEN1 1647/4885KMT2A 3091/4885HTT 1730/4885
US-20080182337-A1 COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF FLUOROPHORES PFAS, PPOX, DHPS MEN1 2741/4885KMT2A 3329/4885HTT 3498/4885
US-10780184-B2 Fluorescent solid lipid nanoparticles composition and preparation thereof LIPA, PLIN3, NPC1L1 MEN1 2586/4885KMT2A 2583/4885HTT 3604/4885
US-20100041158-A1 Lead sensor and methods of use CACYBP, NCS1, PDLIM5 MEN1 3848/4885KMT2A 2427/4885HTT 3749/4885
US-20160106869-A1 FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF LIPA, PLIN3, NPC1L1 MEN1 2586/4885KMT2A 2583/4885HTT 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.