Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 6/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709079 | 0.91 | PRMT1 (0.33) | PRMT1MEN1KMT2AMAPTBLM | |
| SCHEMBL1709074 | 0.89 | FOLH1 (0.32) | FOLH1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL13070158 | 0.83 | PRMT1 (0.44) | FOLH1PRMT1MEN1KMT2ACHRM1 | |
| SCHEMBL1709078 | 0.81 | — | — | |
| SCHEMBL13050797 | 0.77 | PRMT1 (0.38) | FOLH1PRMT1CHRM1CHRM3CHRM2 | |
| SCHEMBL1709073 | 0.76 | MEN1 (0.42) | FOLH1PRMT1MEN1KMT2ACHRM1 | |
| SCHEMBL5651416 | 0.76 | PRMT1 (0.44) | FOLH1PRMT1MEN1KMT2ACHRM1 | |
| SCHEMBL5651412 | 0.76 | PRMT1 (0.44) | FOLH1PRMT1MEN1KMT2ACHRM1 | |
| SCHEMBL1709075 | 0.75 | PRMT1 (0.53) | FOLH1PRMT1MEN1KMT2ACHRM1 | |
| SCHEMBL13050799 | 0.74 | PRMT1 (0.40) | FOLH1PRMT1MEN1KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088262-A1 | CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE | MILLIPORE CORPORATION (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088262-A1 | CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE | CASP7, MCL1, CARS1 | FOLH1 1512/4885PRMT1 684/4885MEN1 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.