Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.37 |
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292857 | 0.84 | RAB9A (0.47) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL779443 | 0.83 | NPC1 (0.58) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL25007291 | 0.82 | KIF11 (0.47) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL22863118 | 0.80 | NPC1 (0.44) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL4603900 | 0.80 | IDO1 (0.39) | NPC1RAB9AMAPTLMNAATM | |
| SCHEMBL25888283 | 0.78 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL12883526 | 0.78 | TSHR (0.48) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL9473731 | 0.77 | ALDH1A1 (0.52) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL21038252 | 0.77 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL19173431 | 0.77 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2012046884-A1 | METHOD FOR PRODUCING OPTICAL FILM, OPTICAL FILM PRODUCED BY THE METHOD, AND POLARIZING PLATE AND IMAGE-FORMING DISPLAY DEVICE HAVING THE FILM | FUJIFILM CORPORATION (JP) | 2012-04-12 | — | — | WO | disclosed |