Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.43 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121857 | 0.82 | LMNA (0.55) | HSP90AA1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL10752030 | 0.82 | LMNA (0.55) | HSP90AA1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL8822078 | 0.82 | LMNA (0.55) | HSP90AA1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL10751742 | 0.78 | LMNA (0.60) | RAB9AHSP90AA1KDM4EMAPK1TDP1 | |
| SCHEMBL16236476 | 0.78 | KMT2A (0.55) | RAB9AKDM4ENPC1TDP1KMT2A | |
| Isopropyl Myristate SCHEMBL27674010 | 0.75 | LMNA (0.59) | RAB9AHSP90AA1KDM4ENPC1MAPK1 | |
| SCHEMBL1699754 | 0.75 | KDM4E (0.59) | KDM4EL3MBTL1LMNAGAA | |
| SCHEMBL10828205 | 0.75 | POLM (0.56) | L3MBTL1LMNASMN1; SMN2GAAPOLM | |
| Hydrochloric Acid SCHEMBL16236349 | 0.74 | KMT2A (0.48) | KDM4ETDP1KMT2AMEN1RECQL | |
| SCHEMBL4457246 | 0.74 | LMNA (0.66) | RAB9AHSP90AA1KDM4ENPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691992-B2 | Octahydro biquinoline compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-04-08 | — | — | US | disclosed |
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | CYP2S1, HCRTR2, CYP2B6 | RAB9A 2786/4885HSP90AA1 4834/4885KDM4E 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.