SCHEMBL170914

SCHEMBL170914

C=CCc1cccc2c1C(=O)NC2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.49
GABRB2 P47870 1/20 0.49
GSK3B P49841 2/20 0.42
AKR1B1 P15121 1/20 0.42
KDM4E B2RXH2 4/20 0.41
GAA P10253 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 1/20 0.41
PARP1 P09874 5/20 0.40
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
ELANE P08246 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL3259478 0.98 GABRA1 (0.47) GABRA1GABRB2GSK3BAKR1B1KDM4E
SCHEMBL16863190 0.86 PARP1 (0.47) GSK3BKDM4EGAAALDH1A1HPGD
SCHEMBL6399903 0.85 GABRA1 (0.45) GABRA1GABRB2GSK3BAKR1B1KDM4E
SCHEMBL709378 0.84 GSK3B (0.43) GSK3BKDM4EGAAALDH1A1HPGD
SCHEMBL6347009 0.84 PARP1 (0.40) GABRA1GABRB2GSK3BKDM4EGAA
SCHEMBL4431549 0.83 GSK3B (0.39) GABRA1GABRB2GSK3BAKR1B1KDM4E
SCHEMBL8518060 0.82 PARP1 (0.53) GABRA1GABRB2GSK3BAKR1B1KDM4E
SCHEMBL5167684 0.80 GSK3B (0.46) GSK3BKDM4EGAAALDH1A1HPGD
SCHEMBL4975651 0.80 PARP1 (0.42) GSK3BKDM4EGAAALDH1A1HPGD
SCHEMBL10416488 0.80 PARP1 (0.42) GSK3BKDM4EGAAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111763433-B Copper chloride phthalocyanine pigment composition for non-bronze plastic coloring and preparation method thereof 绍兴斯慧尔新材料有限公司 2022-02-18 CN claimed
WO-2022000896-A1 CHLORINATED COPPER PHTHALOCYANINE PIGMENT COMPOSITION FOR COLORING NON-BRONZE PLASTICS AND PREPARATION METHOD 绍兴斯慧尔新材料有限公司 2022-01-06 WO claimed
EP-3808359-A1 COMBINATION OF NATURAL ACTIVE INGREDIENTS PROMOTING APOPTOSIS IN DAMAGED OR SUFFERING SKIN TISSUES Valetudo S.r.l. Con Unico Socio (IT) 2021-04-21 EP claimed
CN-111763433-A Copper chloride phthalocyanine pigment composition for non-bronze plastic coloring and preparation method thereof 绍兴斯慧尔新材料有限公司 2020-10-13 CN claimed
CN-109305933-B Method for preparing N-alkyl-4-nitrophthalimide 浙江万丰化工股份有限公司 2020-07-28 CN claimed
CN-110306346-A A kind of refining dye enzyme and preparation method thereof promoting the anti-fuzz balls performance of cotton knitwear 广东湛丰精细化工有限公司 2019-10-08 CN claimed
CN-109944097-A Instrument synthetic fibre PRINTED FABRIC and its printing method 广东溢达纺织有限公司 2019-06-28 CN claimed
CN-106638049-B Asepsis environment-protecting suitable for embedding oxygen polyimide material is plasticized carrier and its application 仪征市海帆化工有限公司 2019-05-17 CN claimed
CN-109305933-A A method of preparing N- alkyl -4- nitrophthalimide 浙江万丰化工有限公司 2019-02-05 CN claimed
CN-208356755-U A kind of esterification structure for the production of N- alkyl phthalic imide 江苏海云花新材料有限公司 2019-01-11 CN claimed
EP-0164409-B1 METHOD FOR MAKING N-SUBSTITUTED NITROPHTHALIMIDES GENERAL ELECTRIC COMPANY (US) 1989-08-02 EP claimed
US-4599429-A Destruction of DNPI in an all nitric acid nitration process GENERAL ELECTRIC COMPANY (US) 1986-07-08 US claimed
EP-0164409-A1 METHOD FOR MAKING N-SUBSTITUTED NITROPHTHALIMIDES. GEN ELECTRIC (US) 1985-12-18 EP claimed
EP-0164410-A1 DESTRUCTION OF DNPI IN AN ALL NITRIC ACID NITRATION PROCESS. GEN ELECTRIC (US) 1985-12-18 EP claimed
EP-0147798-A2 Nitration reactions with acid anhydride promoters GENERAL ELECTRIC COMPANY (US) 1985-07-10 EP claimed
WO-1985002613-A1 DESTRUCTION OF DNPI IN AN ALL NITRIC ACID NITRATION PROCESS GENERAL ELECTRIC COMPANY (US) 1985-06-20 WO claimed
WO-1985002612-A1 METHOD FOR MAKING N-SUBSTITUTED NITROPHTHALIMIDES GENERAL ELECTRIC COMPANY (US) 1985-06-20 WO claimed
US-4467097-A DIPOLAR APROTIC SOLVENT AND ZINC HALIDE AS PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1984-08-21 US claimed
EP-0107542-A1 Method for making aromatic bis(etherimide)s GENERAL ELECTRIC COMPANY (US) 1984-05-02 EP claimed
US-3976427-A Organic compounds SANDOZ LTD. (CH) 1976-08-24 US claimed