Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3259478

C=CCc1cccc2c1C(=O)NC2=O.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
AKR1B1 P15121 1/20 0.41
GSK3B P49841 2/20 0.41
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 4/20 0.40
GAA P10253 3/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
PARP1 P09874 4/20 0.39
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
LMNA P02545 1/20 0.38
CYP2D6 P10635 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
ELANE P08246 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170914 0.98 GABRA1 (0.49) GABRA1GABRB2AKR1B1GSK3BKDM4E
SCHEMBL16863190 0.84 PARP1 (0.47) GSK3BKDM4EALDH1A1GAAHPGD
SCHEMBL6399903 0.84 GABRA1 (0.45) GABRA1GABRB2AKR1B1GSK3BKDM4E
SCHEMBL709378 0.83 GSK3B (0.43) GSK3BKDM4EALDH1A1GAAHPGD
SCHEMBL6347009 0.83 PARP1 (0.40) GABRA1GABRB2GSK3BKDM4EALDH1A1
SCHEMBL4431549 0.82 GSK3B (0.39) GABRA1GABRB2AKR1B1GSK3BKDM4E
SCHEMBL8518060 0.80 PARP1 (0.53) GABRA1GABRB2AKR1B1GSK3BKDM4E
SCHEMBL5167684 0.79 GSK3B (0.46) GSK3BKDM4EALDH1A1GAAHPGD
SCHEMBL10416488 0.79 PARP1 (0.42) GSK3BKDM4EALDH1A1GAAHPGD
SCHEMBL4975651 0.79 PARP1 (0.42) GSK3BKDM4EALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7678850-B2 Pigment dispersions containing aminated acrylic macromonomer dispersant E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-16 US claimed
US-20090012231-A1 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY 2009-01-08 US claimed
US-20070142546-A1 Pigment dispersions containing aminated acrylic macromonomer dispersant AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2007-06-21 US claimed
US-7678850-B2 Pigment dispersions containing aminated acrylic macromonomer dispersant E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-16 US disclosed
US-20090012231-A1 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY 2009-01-08 US disclosed
EP-1966335-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-10 EP disclosed
WO-2007070724-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-21 WO disclosed
US-20070142546-A1 Pigment dispersions containing aminated acrylic macromonomer dispersant AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2007-06-21 US disclosed