SCHEMBL17091625

SCHEMBL17091625

O=C(O)N1CCC(Oc2cc(N3CCc4cc(S(=O)(=O)CCF)ccc43)ncn2)CC1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300112 0.92 GPR119 (0.67) GPR119
SCHEMBL17091622 0.92 GPR119 (0.64) GPR119
SCHEMBL17091636 0.91 GPR119 (0.67) GPR119
SCHEMBL3245324 0.89 GPR119 (0.64) GPR119
SCHEMBL299959 0.87 GPR119 (0.80) GPR119
SCHEMBL3245272 0.85 GPR119 (0.63) GPR119
SCHEMBL17091630 0.85 GPR119 (0.64) GPR119
SCHEMBL3242038 0.84 GPR119 (0.65) GPR119
SCHEMBL3242179 0.83 GPR119 (0.61) GPR119
SCHEMBL3238729 0.82 GPR119 (0.81) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210886-B1 PYRIMIDYL INDOLINE COMPOUND DAIICHI SANKYO CO LTD (JP) 2015-09-23 — — EP claimed
Send feedback