Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17091625 | 0.92 | GPR119 (0.62) | GPR119 | |
| SCHEMBL17091622 | 0.92 | GPR119 (0.64) | GPR119 | |
| SCHEMBL17091636 | 0.91 | GPR119 (0.67) | GPR119 | |
| SCHEMBL3238168 | 0.89 | GPR119 (0.65) | GPR119 | |
| SCHEMBL287689 | 0.89 | GPR119 (0.81) | GPR119 | |
| SCHEMBL299959 | 0.88 | GPR119 (0.80) | GPR119 | |
| SCHEMBL17091630 | 0.85 | GPR119 (0.64) | GPR119 | |
| SCHEMBL3245272 | 0.83 | GPR119 (0.63) | GPR119 | |
| SCHEMBL3236333 | 0.82 | GPR119 (0.65) | GPR119 | |
| SCHEMBL3238729 | 0.82 | GPR119 (0.81) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427448-A1 | Gpr 119 modulators | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128414-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |