Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28378810 | 0.98 | MAOA (0.42) | MAOAGPR3ALDH1A1SMN1; SMN2GSK3B | |
| SCHEMBL16728889 | 0.98 | MAOA (0.45) | MAOAGPR3ALDH1A1SMN1; SMN2GSK3B | |
| SCHEMBL29814962 | 0.98 | MAOA (0.45) | MAOAGPR3ALDH1A1SMN1; SMN2GSK3B | |
| SCHEMBL347425 | 0.98 | MAOA (0.45) | MAOAGPR3ALDH1A1SMN1; SMN2GSK3B | |
| Sulfuric Acid SCHEMBL28551070 | 0.87 | BCHE (0.39) | MAOAALDH1A1SMN1; SMN2GSK3BMEN1 | |
| SCHEMBL11684678 | 0.87 | MAPT (0.41) | MAOAGPR3ALDH1A1SMN1; SMN2GSK3B | |
| SCHEMBL27383055 | 0.86 | BCHE (0.38) | MAOASMN1; SMN2GSK3BMEN1KMT2A | |
| SCHEMBL28285820 | 0.82 | BCHE (0.36) | MAOAALDH1A1SMN1; SMN2GSK3BKDM4E | |
| Quinoline SCHEMBL27619256 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EGAAHPGD | |
| Quinoline SCHEMBL27619364 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707860-A | Triphenylamine and thiazole salt derivatives, fluorescent probe, and preparation method and application thereof | 安徽大学 | 2025-03-28 | — | — | CN | claimed |
| CN-114874638-B | Meso-position substituted pentamethine cyanine dye, preparation method and application thereof, and fluorescent probe | 西安建筑科技大学 | 2024-01-19 | — | — | CN | claimed |
| CN-114874638-A | Meso-position substituted pentamethine cyanine dye, preparation method and application thereof, and fluorescent probe | 西安建筑科技大学 | 2022-08-09 | — | — | CN | claimed |
| CN-105203512-B | A kind of carbazoles fluorescence probe and its preparation method and application | 山西大学 | 2018-02-06 | — | — | CN | claimed |
| CN-105203512-A | Carbazole fluorescent probe and preparation method and application thereof | UNIV SHANXI | 2015-12-30 | — | — | CN | claimed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | claimed |
| CN-1252707-A | Use of unsaturated aldehydes in dying fibers containing keratin | HENKEL KGAA (DE) | 2000-05-10 | — | — | CN | claimed |
| CN-119707860-A | Triphenylamine and thiazole salt derivatives, fluorescent probe, and preparation method and application thereof | 安徽大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-118702692-A | Preparation method of benzothiazole tetrafluoroborate fluorescent dye | 苏州络森生物科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118666862-A | Novel aggregation-induced emission type I photosensitizer molecule and preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2024-09-20 | — | — | CN | disclosed |
| CN-118126032-A | Fluorescent probe and preparation method and application thereof | 广州谱赛生物医学科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-3119610-B1 | ENCRYPTED OPTICAL MARKERS FOR SECURITY APPLICATIONS | APDN BVI INC (VG) | 2024-05-22 | — | — | EP | disclosed |
| CN-117567456-A | Mercury ion fluorescent probe, preparation method thereof and application of visualized traditional Chinese medicine plant mercury absorption | 安徽中医药大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-105203512-A | Carbazole fluorescent probe and preparation method and application thereof | UNIV SHANXI | 2015-12-30 | — | — | CN | disclosed |
| CN-103370312-B | 1,3-diox-5-ketone compound | MERCK PATENT GMBH (DE) | 2015-09-30 | — | — | CN | disclosed |
| WO-2015142990-A1 | ENCRYPED OPTICAL MARKERS FOR SECURITY APPLICATIONS | APDN (B.V.I.) INC. (VG) | 2015-09-24 | — | — | WO | disclosed |
| US-20150266332-A1 | ENCRYPTED OPTICAL MARKERS FOR SECURITY APPLICATIONS | APDN (B.V.I.) INC. (VG) | 2015-09-24 | — | — | US | disclosed |
| CN-103370312-A | 1,3-dioxan-5-one compounds | MERCK PATENT GMBH | 2013-10-23 | — | — | CN | disclosed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | disclosed |
| CN-1252707-A | Use of unsaturated aldehydes in dying fibers containing keratin | HENKEL KGAA (DE) | 2000-05-10 | — | — | CN | disclosed |