Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709431 | 0.90 | MAOB (0.45) | MAOBKDM1ACCRL2ATMMAOA | |
| SCHEMBL1709352 | 0.90 | MAOB (0.45) | MAOBKDM1ACCRL2ATMMAOA | |
| SCHEMBL1709351 | 0.90 | KDM1A (0.42) | MAOBKDM1ACCRL2 | |
| SCHEMBL10032966 | 0.79 | MAOA (0.35) | MAOBKDM1ACCRL2FFAR1MAOA | |
| SCHEMBL10032825 | 0.76 | KDM1A (0.38) | MAOBKDM1AALDH1A1KDM4EMAOA | |
| SCHEMBL10033117 | 0.75 | KDM1A (0.44) | MAOBKDM1AALDH1A1KDM4EMAOA | |
| SCHEMBL10188552 | 0.75 | DGAT1 (0.46) | GAAALDH1A1KDM4ECCRL2MAPT | |
| SCHEMBL10033107 | 0.73 | KDM1A (0.45) | MAOBKDM1AMAOATDP1 | |
| SCHEMBL1709393 | 0.72 | KDM4E (0.38) | GAAALDH1A1KDM4EMAPTCYP11B1 | |
| SCHEMBL1709416 | 0.72 | KDM1A (0.44) | MAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |