Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033107 | 0.85 | KDM1A (0.45) | KDM1ARCOR1MAOB | |
| SCHEMBL1709421 | 0.81 | L3MBTL1 (0.38) | KDM1AHDAC6L3MBTL1SIGMAR1 | |
| SCHEMBL10032974 | 0.77 | SIGMAR1 (0.44) | KDM1AHDAC6RCOR1MAOBSIGMAR1 | |
| SCHEMBL10033114 | 0.74 | KDM1A (0.42) | KDM1AL3MBTL1MAOB | |
| SCHEMBL10032825 | 0.73 | KDM1A (0.38) | KDM1ARCOR1MAOBSIGMAR1 | |
| SCHEMBL1709353 | 0.72 | MAOB (0.44) | KDM1AMAOB | |
| SCHEMBL1709384 | 0.71 | SIGMAR1 (0.40) | KDM1AHDAC6L3MBTL1SIGMAR1 | |
| SCHEMBL10033177 | 0.71 | GRIA4 (0.38) | KDM1AHDAC6SIGMAR1 | |
| SCHEMBL10033108 | 0.71 | L3MBTL1 (0.37) | HDAC6L3MBTL1 | |
| SCHEMBL10032840 | 0.71 | L3MBTL1 (0.37) | HDAC6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |