Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10248636 | 0.92 | ALDH1A1 (0.40) | ALDH1A1POLBMAPTTDP1ITGB3 | |
| SCHEMBL10248672 | 0.72 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTTDP1ITGB3 | |
| SCHEMBL28827330 | 0.71 | PPARD (0.39) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL14101862 | 0.71 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTTDP1ITGB3 | |
| SCHEMBL10248614 | 0.69 | — | — | |
| SCHEMBL9060863 | 0.64 | ITGB1 (0.43) | ALDH1A1POLBMAPTTDP1ITGB3 | |
| SCHEMBL630436 | 0.64 | ITGB1 (0.54) | ALDH1A1POLBMAPTTDP1ITGB3 | |
| SCHEMBL2733481 | 0.63 | ITGB3 (0.38) | ALDH1A1POLBMAPTTDP1ITGB3 | |
| SCHEMBL17519894 | 0.63 | — | — | |
| SCHEMBL8652310 | 0.63 | GAA (0.44) | ALDH1A1POLBTDP1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |