Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917416 | 0.88 | MDM2 (0.48) | MDM2TP53SLC6A4SLC6A3 | |
| SCHEMBL28817040 | 0.79 | IDO1 (0.56) | MDM2TP53SLC6A3 | |
| SCHEMBL1709367 | 0.76 | MEN1 (0.46) | MDM2TP53 | |
| SCHEMBL6918303 | 0.75 | KDM1A (0.47) | SLC6A4SLC6A3 | |
| SCHEMBL3554788 | 0.74 | HDAC8 (0.50) | — | |
| SCHEMBL6918804 | 0.73 | KDM4E (0.45) | — | |
| SCHEMBL27405518 | 0.72 | SLC6A4 (0.49) | SLC6A4SLC6A3 | |
| SCHEMBL1709371 | 0.71 | MEN1 (0.43) | MDM2TP53 | |
| SCHEMBL22498237 | 0.70 | BRD4 (0.39) | — | |
| SCHEMBL3408659 | 0.70 | BRD4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |