Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709360 | 0.88 | L3MBTL1 (0.43) | MEN1KMT2ATP53MDM2HPGD | |
| SCHEMBL6917416 | 0.88 | MDM2 (0.48) | TP53MDM2 | |
| SCHEMBL1709472 | 0.86 | DGAT1 (0.39) | SMN1; SMN2 | |
| SCHEMBL1709495 | 0.85 | MEN1 (0.38) | MEN1KMT2ATP53MDM2ABCC1 | |
| SCHEMBL1709371 | 0.82 | MEN1 (0.43) | MEN1KMT2ATP53MDM2ABCC1 | |
| SCHEMBL1709417 | 0.81 | DPP4 (0.42) | MEN1KMT2AHPGDDPP4 | |
| SCHEMBL10032839 | 0.80 | KDM1A (0.40) | TP53MDM2DPP4 | |
| SCHEMBL10032838 | 0.78 | TP53 (0.40) | MEN1KMT2ATP53MDM2SMN1; SMN2 | |
| SCHEMBL15798206 | 0.78 | HTR2A (0.47) | MEN1KMT2AABCC1HPGDSMN1; SMN2 | |
| SCHEMBL17259159 | 0.78 | HTR2A (0.47) | MEN1KMT2AABCC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |