Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032838 | 0.88 | TP53 (0.40) | MEN1KMT2ATP53MDM2SMN1; SMN2 | |
| SCHEMBL1709367 | 0.82 | MEN1 (0.46) | MEN1KMT2ATP53MDM2ABCC1 | |
| SCHEMBL1709437 | 0.77 | PTGES (0.37) | KMT2ATP53NPSR1 | |
| SCHEMBL10033115 | 0.77 | MDM2 (0.43) | TP53MDM2 | |
| SCHEMBL1709421 | 0.75 | L3MBTL1 (0.38) | MEN1KMT2ATP53MDM2 | |
| SCHEMBL15798206 | 0.75 | HTR2A (0.47) | MEN1KMT2AABCC1HPGDSMN1; SMN2 | |
| SCHEMBL17259159 | 0.75 | HTR2A (0.47) | MEN1KMT2AABCC1HPGDSMN1; SMN2 | |
| SCHEMBL1709507 | 0.75 | MEN1 (0.44) | MEN1KMT2ATP53ABCC1HPGD | |
| SCHEMBL6916644 | 0.72 | MDM2 (0.40) | TP53MDM2DRD2OPRM1DRD3 | |
| SCHEMBL13964536 | 0.72 | DRD2 (0.45) | TP53MDM2DRD2OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |