Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20967239 | 1.00 | TSHR (0.43) | TSHRALDH1A1PDE3BPDE3AHDAC2 | |
| SCHEMBL15834804 | 0.93 | ALDH1A1 (0.44) | TSHRALDH1A1PDE3BPDE3AHDAC2 | |
| SCHEMBL1942123 | 0.87 | TSHR (0.43) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL28566500 | 0.85 | PTGS1 (0.49) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL15077185 | 0.85 | PTGS1 (0.49) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL2140807 | 0.85 | PTGS1 (0.49) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL172021 | 0.85 | PDE3B (0.41) | ALDH1A1PDE3BPDE3APTGS1PTGS2 | |
| SCHEMBL4427979 | 0.85 | PDE3B (0.41) | ALDH1A1PDE3BPDE3APTGS1PTGS2 | |
| SCHEMBL13239279 | 0.84 | ALDH1A1 (0.39) | TSHRALDH1A1HDAC2ALOX5APFEN1 | |
| SCHEMBL13412045 | 0.84 | ALDH1A1 (0.39) | TSHRALDH1A1HDAC2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906662-B1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |
| US-10056548-B2 | Emitter and hosts with aromatic units | MERCK PATENT GMBH (DE) | 2018-08-21 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |