Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099320 | 1.00 | TSHR (0.43) | TSHRALDH1A1PDE3BPDE3AHDAC2 | |
| SCHEMBL15834804 | 0.93 | ALDH1A1 (0.44) | TSHRALDH1A1PDE3BPDE3AHDAC2 | |
| SCHEMBL1942123 | 0.87 | TSHR (0.43) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL28566500 | 0.85 | PTGS1 (0.49) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL15077185 | 0.85 | PTGS1 (0.49) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL2140807 | 0.85 | PTGS1 (0.49) | TSHRALDH1A1PDE3BPDE3APTGS1 | |
| SCHEMBL172021 | 0.85 | PDE3B (0.41) | ALDH1A1PDE3BPDE3APTGS1PTGS2 | |
| SCHEMBL4427979 | 0.85 | PDE3B (0.41) | ALDH1A1PDE3BPDE3APTGS1PTGS2 | |
| SCHEMBL13239279 | 0.84 | ALDH1A1 (0.39) | TSHRALDH1A1HDAC2ALOX5APFEN1 | |
| SCHEMBL13412045 | 0.84 | ALDH1A1 (0.39) | TSHRALDH1A1HDAC2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667845-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-03-02 | — | — | US | disclosed |
| US-20230056437-A1 | AZO DYE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-11352560-B2 | Liquid crystal mixture and liquid crystal display | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-20210130693-A1 | Liquid Crystal Mixture and Liquid Crystal Display | MERCK PATENT GMBH (DE) | 2021-05-06 | — | — | US | disclosed |
| US-10982149-B2 | Chiral compounds | MERCK PATENT GMBH (DE) | 2021-04-20 | — | — | US | disclosed |
| US-20210102122-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2021-04-08 | — | — | US | disclosed |
| US-20190127642-A1 | COMPOSITION FOR NANOENCAPSULATION AND NANOCAPSULES COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10982149-B2 | Chiral compounds | FANCI, COL1A1, LCP1 | TSHR 1809/4885ALDH1A1 371/4885PDE3B 942/4885 |
| US-11667845-B2 | Liquid crystalline medium | NEFM, CCNI, MYT1 | TSHR 3699/4885ALDH1A1 1933/4885PDE3B 1552/4885 |
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | CXCR1, PYM1, F11 | TSHR 3248/4885ALDH1A1 2963/4885PDE3B 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.