Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.35 |
| ▸ | CTSD | P07339 | 3/20 | 0.35 |
| ▸ | CTSE | P14091 | 3/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16549357 | 0.88 | BACE1 (0.38) | BACE1CTSDCTSE | |
| SCHEMBL16549401 | 0.88 | BACE1 (0.38) | BACE1CTSDCTSE | |
| SCHEMBL23056409 | 0.86 | — | — | |
| SCHEMBL17226012 | 0.84 | MMP1 (0.33) | BACE1CTSDCTSE | |
| SCHEMBL17919865 | 0.82 | SLC7A5 (0.31) | — | |
| SCHEMBL17920239 | 0.79 | BACE1 (0.36) | BACE1CTSDCTSE | |
| SCHEMBL17920254 | 0.77 | BACE1 (0.32) | BACE1CTSDCTSE | |
| SCHEMBL17518338 | 0.77 | BACE1 (0.33) | BACE1CTSDCTSE | |
| SCHEMBL17919860 | 0.77 | BACE1 (0.35) | BACE1CTSDCTSE | |
| SCHEMBL18737337 | 0.76 | BACE1 (0.39) | BACE1CTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088734-A1 | Cyclosporin Analogs | ALLERGAN, INC. (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088734-A1 | Cyclosporin Analogs | CHP1, TSLP, PPP3R1 | BACE1 2709/4885CTSD 504/4885CTSE 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.