Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102066 | 0.92 | STS (0.55) | CYP3A4MEN1KMT2AMMP1MMP9 | |
| SCHEMBL26064727 | 0.87 | TGM2 (0.47) | CYP3A4MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL18153290 | 0.86 | PKM (0.66) | MMP1MMP9PKMNPC1PKLR | |
| SCHEMBL17101977 | 0.84 | CYP3A4 (0.65) | CYP3A4MEN1KMT2APKMNPC1 | |
| SCHEMBL17102104 | 0.84 | PKM (0.71) | CYP3A4MEN1KMT2APKMNPC1 | |
| SCHEMBL17102096 | 0.81 | CYP3A4 (0.62) | CYP3A4MEN1KMT2APKMNPC1 | |
| SCHEMBL17101969 | 0.81 | CYP3A4 (0.64) | CYP3A4MEN1KMT2APKMNPC1 | |
| SCHEMBL17101980 | 0.79 | ALDH1A1 (0.58) | CYP3A4MEN1KMT2APKMNPC1 | |
| SCHEMBL17102082 | 0.79 | CYP3A4 (0.59) | CYP3A4MEN1KMT2APKMNPC1 | |
| SCHEMBL17102110 | 0.78 | CYP3A4 (0.56) | CYP3A4MEN1KMT2APKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140400-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2020-05-07 | — | — | US | disclosed |
| US-10562869-B2 | Oxadiazole compounds | REMYND NV (BE) | 2020-02-18 | — | — | US | disclosed |
| EP-3119782-B1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | REMYND NV (BE) | 2018-01-31 | — | — | EP | disclosed |
| US-9750745-B2 | 2,7-diazaspiro[3.5]nonane compounds | REMYND NV (BE) | 2017-09-05 | — | — | US | disclosed |
| US-20170157137-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | REMYND NV (BE) | 2017-06-08 | — | — | US | disclosed |
| US-9617264-B2 | 2,7-diazaspiro[3.5]nonane compounds | REMYND NV (BE) | 2017-04-11 | — | — | US | disclosed |
| US-20170073319-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2017-03-16 | — | — | US | disclosed |
| EP-3119774-A1 | OXADIAZOLE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| EP-3119782-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| US-20170015665-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | REMYND NV (BE) | 2017-01-19 | — | — | US | disclosed |
| WO-2015140130-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |
| WO-2015140132-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157137-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | PSEN1, MAPT, PSEN2 | CYP3A4 1773/4885MEN1 1633/4885KMT2A 4531/4885 |
| US-10562869-B2 | Oxadiazole compounds | OXA1L, PSEN1, MAPT | CYP3A4 738/4885MEN1 2665/4885KMT2A 4820/4885 |
| US-20170015665-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | PSEN1, MAPT, PSEN2 | CYP3A4 1773/4885MEN1 1633/4885KMT2A 4531/4885 |
| US-20200140400-A1 | OXADIAZOLE COMPOUNDS | OXA1L, PSEN1, MAPT | CYP3A4 847/4885MEN1 2837/4885KMT2A 4819/4885 |
| US-20170073319-A1 | OXADIAZOLE COMPOUNDS | OXA1L, PSEN1, MAPT | CYP3A4 738/4885MEN1 2665/4885KMT2A 4820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.