Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29285993 | 0.88 | CYP19A1 (0.63) | ALDH1A1MAPTGAARECQLMEN1 | |
| SCHEMBL30989152 | 0.88 | CYP19A1 (0.63) | ALDH1A1MAPTGAARECQLMEN1 | |
| SCHEMBL12030446 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MAPTGAARECQLSMN1; SMN2 | |
| SCHEMBL17101738 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MAPTGAARECQLSMN1; SMN2 | |
| SCHEMBL17101705 | 0.83 | KMT2A (0.59) | ALDH1A1MAPTRECQLKMT2AHTT | |
| SCHEMBL17101822 | 0.80 | HSD11B1 (0.61) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17101814 | 0.79 | SMN1; SMN2 (0.72) | ALDH1A1MAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL17101803 | 0.79 | CYP19A1 (0.66) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL5606903 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTGAARECQLMEN1 | |
| SCHEMBL27734520 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTGAARECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015140566-A1 | PYRAZOLO-PYRIMIDINES AS INHIBITORS OF BTK | REDX PHARMA PLC (GB) | 2015-09-24 | — | — | WO | disclosed |