Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | MECP2 | P51608 | 1/20 | 0.47 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.47 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.47 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.47 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279571 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPK10GFERGAA | |
| SCHEMBL30496474 | 0.80 | SYK (0.41) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL16388214 | 0.80 | SYK (0.41) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL31627855 | 0.78 | KDM4E (0.48) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL2501726 | 0.74 | KMT2A (0.70) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL5771649 | 0.74 | MAPK10 (0.70) | MEN1KMT2AMAPK10GFERLMNA | |
| SCHEMBL18936841 | 0.73 | MEN1 (0.53) | MEN1KMT2AMAPK10GFERMECP2 | |
| SCHEMBL29391624 | 0.73 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERMECP2 | |
| SCHEMBL221242 | 0.73 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERMECP2 | |
| SCHEMBL30167997 | 0.73 | MEN1 (0.76) | MEN1KMT2AMAPK10GFERKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145391-B2 | Bipyridylaminopyridines as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-09-29 | — | — | US | disclosed |