SCHEMBL17102987

SCHEMBL17102987

O=C(Nc1ccccc1)Nc1ccccc1NS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.60
▸ NPC1 O15118 1/20 0.60
▸ RAB9A P51151 1/20 0.60
▸ CA2 P00918 1/20 0.58
▸ GAA P10253 2/20 0.56
▸ GPR27 Q9NS67 1/20 0.55
▸ LMNA P02545 4/20 0.55
▸ MEN1 O00255 4/20 0.55
▸ KMT2A Q03164 4/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ ALDH1A1 P00352 2/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ SLC16A3 O15427 3/20 0.52
▸ PGR P06401 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12010908 0.84 GAA (0.66) MAPTNPC1RAB9ACA2GAA
SCHEMBL7770159 0.82 LMNA (0.64) MAPTNPC1RAB9ACA2GAA
SCHEMBL17103006 0.81 MEN1 (0.64) MAPTCA2GAAGPR27LMNA
SCHEMBL15145840 0.81 LMNA (0.70) MAPTCA2GAALMNAMEN1
SCHEMBL6077413 0.81 NPC1 (0.62) MAPTNPC1RAB9ACA2GAA
SCHEMBL17103024 0.81 TUBB4A (0.60) MAPTNPC1RAB9AGAALMNA
SCHEMBL17103025 0.81 MEN1 (0.63) MAPTNPC1RAB9ACA2GAA
SCHEMBL20568030 0.80 LMNA (0.61) MAPTGAALMNAMEN1KMT2A
SCHEMBL29895854 0.80 LMNA (0.61) MAPTGAALMNAMEN1KMT2A
SCHEMBL17103022 0.80 KMT2A (0.67) MAPTNPC1RAB9AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2923851-B1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO (JP) 2019-05-01 — — EP disclosed
US-9518011-B2 Recording material produced using non-phenol compound NIPPON SODA CO., LTD. (JP) 2016-12-13 — — US disclosed
US-9518011-B2 Recording material produced using non-phenol compound NIPPON SODA CO., LTD. (JP) 2016-12-13 — — US disclosed
US-20150284321-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO., LTD. (JP) 2015-10-08 — — US disclosed
US-20150284321-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO., LTD. (JP) 2015-10-08 — — US disclosed
EP-2923851-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND Nippon Soda Co., Ltd. (JP) 2015-09-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284321-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND CYP19A1, ALPG, ALPP MAPT 3343/4885NPC1 2944/4885RAB9A 1790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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