SCHEMBL17102995

SCHEMBL17102995

CCCc1cc(C(C)(C)C)c(O)c(Cc2c(C)ccc(C(C)(C)C)c2O)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 6/20 0.49
CYP2C9 P11712 5/20 0.49
HIF1A Q16665 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
TP53 P04637 2/20 0.49
HSPA5 P11021 2/20 0.39
CYP2D6 P10635 3/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 2/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CA2 P00918 3/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
TYR P14679 1/20 0.34
LMNA P02545 2/20 0.34
CYP3A4 P08684 2/20 0.34
HTR1A P08908 2/20 0.34
ADRA2A P08913 2/20 0.34
KMT2A Q03164 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL753473 0.81 CYP2C19 (0.50) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL29650379 0.81 CYP2C19 (0.50) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL30337501 0.78 CYP2C19 (0.62) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL2165152 0.74 GABRA1 (0.50) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL28365843 0.74 CYP2C9 (0.45) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL7749757 0.74 CYP2C19 (0.60) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL23941079 0.72 GABRA1 (0.48) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL29836467 0.72 GABRA1 (0.48) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL30402247 0.72 GABRA1 (0.48) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53
SCHEMBL9768525 0.72 CYP2C19 (0.68) CYP2C19CYP2C9HIF1ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2923851-B1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO (JP) 2019-05-01 EP disclosed
EP-2923851-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND Nippon Soda Co., Ltd. (JP) 2015-09-30 EP disclosed