Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17103171 | 0.85 | MAPT (0.47) | RORCMAPTALDH1A1HDAC1HDAC3 | |
| SCHEMBL17103220 | 0.84 | KMT2A (0.54) | RORCMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17228260 | 0.84 | MEN1 (0.51) | RORCMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13265843 | 0.84 | RORC (0.59) | RORCMAPTALDH1A1HDAC1HDAC3 | |
| SCHEMBL21301505 | 0.84 | MAPT (0.49) | RORCMAPTALDH1A1HDAC1KMT2A | |
| SCHEMBL17103186 | 0.83 | MEN1 (0.50) | MAPTALDH1A1KMT2ASMN1; SMN2PDE7A | |
| SCHEMBL29430118 | 0.81 | MEN1 (0.53) | RORCMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17103173 | 0.81 | MEN1 (0.53) | RORCMAPTALDH1A1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17103200 | 0.81 | MEN1 (0.52) | RORCMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17228264 | 0.79 | MEN1 (0.50) | MAPTALDH1A1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2924021-B1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | UNIV SICHUAN (CN) | 2019-08-28 | — | — | EP | disclosed |
| US-9402819-B2 | Anti-HIV compound and preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-9402819-B2 | Anti-HIV compound and preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-9402819-B2 | Anti-HIV compound and preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-11-05 | — | — | US | disclosed |
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-11-05 | — | — | US | disclosed |
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-11-05 | — | — | US | disclosed |
| EP-2924021-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | Sichuan University (CN) | 2015-09-30 | — | — | EP | disclosed |
| EP-2924021-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | Sichuan University (CN) | 2015-09-30 | — | — | EP | disclosed |
| CN-103183625-B | Anti-HIV compound and preparation method and application thereof | UNIV SICHUAN | 2015-07-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | FURIN, CD4, SI | RORC 1024/4885MAPT 3953/4885ALDH1A1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.