Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17107204 | 0.89 | ALDH1A1 (0.66) | ALDH1A1MAPTTHRBHPGDSMN1; SMN2 | |
| SCHEMBL17131992 | 0.89 | ALDH1A1 (0.71) | ALDH1A1MAPTTHRBNPC1HPGD | |
| SCHEMBL17107190 | 0.88 | ADORA3 (0.71) | ALDH1A1MAPTTHRBNPC1HPGD | |
| SCHEMBL2754062 | 0.88 | MAPT (0.83) | ALDH1A1MAPTTHRBNPC1HPGD | |
| SCHEMBL2753571 | 0.87 | ALDH1A1 (0.85) | ALDH1A1MAPTTHRBNPC1HPGD | |
| SCHEMBL17107224 | 0.86 | SMN1; SMN2 (0.71) | ALDH1A1MAPTTHRBHPGDSMN1; SMN2 | |
| SCHEMBL17107107 | 0.86 | MEN1 (0.66) | ALDH1A1MAPTTHRBNPC1HPGD | |
| SCHEMBL12300959 | 0.84 | LMNA (0.67) | ALDH1A1MAPTTHRBHPGDSMN1; SMN2 | |
| SCHEMBL2754044 | 0.84 | MAPT (0.70) | ALDH1A1MAPTTHRBNPC1HPGD | |
| SCHEMBL17107205 | 0.84 | NPC1 (0.57) | ALDH1A1MAPTTHRBNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | XAVIER UNIVERSITY OF LOUISIANA | 2015-10-01 | — | — | US | claimed |
| US-20210330646-A1 | FASCIN BINDING COMPOUNDS FOR SPINOGENESIS | SPINOGENIX, INC. | 2021-10-28 | — | — | US | disclosed |
| US-9650369-B2 | Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease | XAVIER UNIVERSITY OF LOUISIANA (US) | 2017-05-16 | — | — | US | disclosed |
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | XAVIER UNIVERSITY OF LOUISIANA | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | MKI67, MIF, NUDC | ALDH1A1 1082/4885MAPT 3002/4885THRB 1531/4885 |
| US-20210330646-A1 | FASCIN BINDING COMPOUNDS FOR SPINOGENESIS | FSCN1, SMN1; SMN2, DCX | ALDH1A1 3791/4885MAPT 410/4885THRB 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.