Noraristeromycin

Noraristeromycin

SCHEMBL17109603

Nc1ncnc2c1ncn2[C@@H]1C[C@H](O)[C@H](O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AHCY P23526 16/20 1.00
ADORA2B P29275 1/20 0.72
ADORA3 P0DMS8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Noraristeromycin SCHEMBL19644993 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL8886019 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL1231088 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL26381984 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL17117186 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL29378522 1.00 AHCY (1.00) AHCYADORA2BADORA3
SCHEMBL12149495 0.93 AHCY (0.86) AHCYADORA2BADORA3
SCHEMBL14635767 0.87 AHCY (1.00) AHCYADORA2B
SCHEMBL17302275 0.86 AHCY (1.00) AHCYADORA2B
SCHEMBL26382107 0.86 AHCY (1.00) AHCYADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150266918-A1 Bridged-Cyclo-ProTides as Prodrugs of Therapeutic Nucleosides and Nucleotides ZHONG MINGHONG (US) 2015-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266918-A1 Bridged-Cyclo-ProTides as Prodrugs of Therapeutic Nucleosides and Nucleotides TYMP, ENPP3, PNP AHCY 3087/4885ADORA2B 147/4885ADORA3 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.