Noraristeromycin

Noraristeromycin

SCHEMBL1231088

Nc1ncnc2c1ncn2[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AHCY P23526 16/20 1.00
ADORA2B P29275 1/20 0.72
ADORA3 P0DMS8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Noraristeromycin SCHEMBL19644993 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL8886019 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL26381984 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL17117186 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL17109603 1.00 AHCY (1.00) AHCYADORA2BADORA3
Noraristeromycin SCHEMBL29378522 1.00 AHCY (1.00) AHCYADORA2BADORA3
SCHEMBL12149495 0.93 AHCY (0.86) AHCYADORA2BADORA3
SCHEMBL14635767 0.87 AHCY (1.00) AHCYADORA2B
SCHEMBL17302275 0.86 AHCY (1.00) AHCYADORA2B
SCHEMBL26382107 0.86 AHCY (1.00) AHCYADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 EP disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 US disclosed
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels ASCENDIS PHARMA A/S (DE) 2023-01-24 US disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 EP disclosed
CN-113512587-B Marker for cancer cell drug resistance, preparation combination for reversing cancer cell drug resistance and application thereof 华中科技大学同济医学院附属同济医院 2022-03-18 CN disclosed
EP-3592393-B1 RELEASABLE CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2021-12-01 EP disclosed
CN-113512587-A Marker for cancer cell drug resistance, preparation combination for reversing cancer cell drug resistance and application thereof 华中科技大学同济医学院附属同济医院 2021-10-19 CN disclosed
WO-2013024048-A1 POLYMERIC HYPERBRANCHED CARRIER-LINKED PRODRUGS ASCENDIS PHARMA A/S (DK) 2013-02-21 WO disclosed
WO-2013024049-A1 PROTEIN CARRIER-LINKED PRODRUGS ASCENDIS PHARMA A/S (DK) 2013-02-21 WO disclosed
EP-2486925-A1 THERAPEUTIC AGENT FOR CEREBRAL INFARCTION Mitsubishi Tanabe Pharma Corporation (JP) 2012-08-15 EP disclosed
US-20120196824-A1 THERAPEUTIC AGENT FOR CEREBRAL INFARCTION MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-08-02 US disclosed
US-20120156259-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2012-06-21 US disclosed
EP-2459220-A1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS Ascendis Pharma A/S (DK) 2012-06-06 EP disclosed
WO-2011089216-A1 DIPEPTIDE-BASED PRODRUG LINKERS FOR ALIPHATIC AMINE-CONTAINING DRUGS ASCENDIS PHARMA AS (DK) 2011-07-28 WO disclosed
WO-2011012715-A1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2011-02-03 WO disclosed
JP-2007099702-A NF-kappaB INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME NAGOYA CITY UNIV 2007-04-19 JP disclosed
WO-1996020010-A1 COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC ORIDIGM CORPORATION (US) 1996-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120156259-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 AHCY 412/4885ADORA2B 4314/4885ADORA3 3686/4885
US-20120196824-A1 THERAPEUTIC AGENT FOR CEREBRAL INFARCTION FABP7, TIMP3, MMP11 AHCY 4108/4885ADORA2B 1681/4885ADORA3 1608/4885
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 AHCY 412/4885ADORA2B 4314/4885ADORA3 3686/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 AHCY 1436/4885ADORA2B 228/4885ADORA3 710/4885
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels PLG, PHYKPL, PLOD3 AHCY 412/4885ADORA2B 4314/4885ADORA3 3686/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 AHCY 1436/4885ADORA2B 228/4885ADORA3 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.