Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 7/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369400 | 0.93 | HSD11B1 (0.43) | SLC34A1P2RX7HSD11B1ABCB11PTGS1 | |
| SCHEMBL170786 | 0.93 | HSD11B1 (0.43) | SLC34A1P2RX7HSD11B1ABCB11PTGS1 | |
| SCHEMBL175809 | 0.92 | LCK (0.41) | SLC34A1P2RX7HSD11B1GRM5PGR | |
| SCHEMBL171531 | 0.90 | HSD11B1 (0.36) | SLC34A1P2RX7HSD11B1ABCB11PTGS1 | |
| SCHEMBL29355021 | 0.90 | HSD11B1 (0.36) | SLC34A1P2RX7HSD11B1ABCB11PTGS1 | |
| SCHEMBL170946 | 0.88 | SLC34A1 (0.42) | SLC34A1P2RX7HSD11B1PGRNR3C2 | |
| SCHEMBL175783 | 0.88 | HSD11B1 (0.42) | SLC34A1P2RX7HSD11B1MAPT | |
| SCHEMBL175938 | 0.88 | SLC34A1 (0.38) | SLC34A1P2RX7GRM5PGRNR3C2 | |
| SCHEMBL29367611 | 0.88 | HSD11B1 (0.42) | SLC34A1P2RX7HSD11B1MAPT | |
| SCHEMBL28135751 | 0.87 | P2RX7 (0.41) | SLC34A1P2RX7HSD11B1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | claimed |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2015-10-29 | — | — | US | claimed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | claimed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | claimed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | claimed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | claimed |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | disclosed |
| US-9596853-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2015-10-29 | — | — | US | disclosed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | SLC34A1 1917/4885P2RX7 710/4885HSD11B1 1540/4885 |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | SLC34A1 1917/4885P2RX7 710/4885HSD11B1 1540/4885 |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | SLC34A1 1917/4885P2RX7 710/4885HSD11B1 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.