Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17112686 | 0.85 | TRPA1 (0.66) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15638403 | 0.85 | TRPA1 (0.66) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17112650 | 0.85 | TRPA1 (0.66) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17110907 | 0.84 | TRPA1 (0.69) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17110876 | 0.84 | TRPA1 (0.69) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17112664 | 0.84 | TRPA1 (0.69) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17110879 | 0.83 | TRPA1 (0.41) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17110871 | 0.83 | TRPA1 (0.41) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17110958 | 0.83 | TRPA1 (0.41) | TRPA1POLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17110870 | 0.82 | TRPA1 (0.41) | TRPA1POLBALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015144977-A1 | TRPA1 MODULATORS | ORIEN CORPORATION (FI) | 2015-10-01 | — | — | WO | claimed |
| WO-2015144977-A1 | TRPA1 MODULATORS | ORIEN CORPORATION (FI) | 2015-10-01 | — | — | WO | disclosed |