Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 3/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17110953 | 0.82 | NR2F2 (0.45) | MAPK8ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL17110968 | 0.80 | MAPK8 (0.43) | MAPK8GBA1HCAR3MAPK1SYK | |
| SCHEMBL23620562 | 0.79 | MAPK8 (0.49) | MAPK8GBA1HCAR3MAPK1SYK | |
| SCHEMBL15636147 | 0.78 | HSD11B1 (0.48) | MAPK8GBA1CYP1A2ALDH1A1HIF1A | |
| SCHEMBL14574985 | 0.75 | RPS6KB1 (0.57) | — | |
| SCHEMBL9931421 | 0.75 | MAPT (0.43) | MAPK8HCAR3MAPK1IDH1CYP3A4 | |
| SCHEMBL14574930 | 0.73 | IRAK4 (0.42) | MAPK1 | |
| SCHEMBL17110960 | 0.73 | MAPK8 (0.39) | MAPK8HCAR3MAPK1IDH1KDM5A | |
| SCHEMBL17110967 | 0.71 | TRPA1 (0.49) | CYP1A2ALDH1A1HIF1AIDH1CYP3A4 | |
| Niacinamide SCHEMBL17110973 | 0.70 | GBA1 (0.44) | MAPK8GBA1SYKKDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015144977-A1 | TRPA1 MODULATORS | ORIEN CORPORATION (FI) | 2015-10-01 | — | — | WO | disclosed |