Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17115360 | 1.00 | G6PD (0.36) | G6PDKDM4EATML3MBTL1MAT2A | |
| SCHEMBL18707156 | 1.00 | G6PD (0.36) | G6PDKDM4EATML3MBTL1MAT2A | |
| SCHEMBL17115339 | 1.00 | G6PD (0.36) | G6PDKDM4EATML3MBTL1MAT2A | |
| SCHEMBL17115375 | 1.00 | G6PD (0.36) | G6PDKDM4EATML3MBTL1MAT2A | |
| SCHEMBL18713352 | 0.95 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115388 | 0.95 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL17115364 | 0.95 | G6PD (0.36) | G6PDMAT2AIRAK4TDP2MAP4K4 | |
| SCHEMBL17115319 | 0.95 | G6PD (0.36) | G6PDKDM4EATML3MBTL1IRAK4 | |
| SCHEMBL18707234 | 0.94 | USP14 (0.33) | G6PDKDM4EATML3MBTL1MAT2A | |
| SCHEMBL18713827 | 0.93 | G6PD (0.39) | G6PDKDM4EATML3MBTL1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| WO-2015140073-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | DBF4, DDT, SLC43A3 | G6PD 1474/4885KDM4E 2610/4885ATM 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.